Structural imaging is insensitive for detecting the disease process in its early stages
and assessing its response after various therapeutic interventions.
Keywords
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References
- Scintillation camera.Rev Sci Instrum. 1958; 29: 27-33
- Computerized transverse axial scanning (tomography). 1. Description of system.Br J Radiol. 1973; 46: 1016-1022
- Studies of central nervous system disorders with single photon emission computed tomography and positron emission tomography: evolution over the past 2 decades.Semin Nucl Med. 1991; 21: 58-81
- Guest editorial: the conception of FDG-PET imaging.Semin Nucl Med. 2002; 32: 2-5
- A positron-emission transaxial tomograph for nuclear imaging (PETT).Radiology. 1975; 114: 89-98
- Image formation by induced local interactions: examples employing nuclear magnetic resonance.Nature. 1973; 242: 190-191
- Iron oxide MR contrast agents for molecular and cellular imaging.NMR Biomed. 2004; 17 (John Wiley & Sons, Ltd.): 484-499
- Potential toxicity of superparamagnetic iron oxide nanoparticles (SPION).Nano Rev. 2010; 1 (CoAction Publishing)https://doi.org/10.3402/nano.v1i0.5358
- PET/CT scanner instrumentation, challenges, and solutions.Radiol Clin North Am. 2004; 42 (vii): 1017-1032
- PET/MR imaging: clinical applications.PET Clin. 2016; 11: xi-xii
- The role of PET in evaluating atherosclerosis: a critical review.Semin Nucl Med. 2018; 48: 488-497
Ingvar D, Lassen N. Quantitative determination of regional cerebral blood-flow in man. Lancet 1961;278:806–7. Elsevier.
- Glial biomarkers in human central nervous system disease.Glia. 2016; 64: 1755-1771
- Computed tomography use for adults with head injury: describing likely avoidable emergency department imaging based on the Canadian CT Head Rule.Acad Emerg Med. 2017; 24: 22-30
- Potential of PET/CT in assessing dementias with emphasis on cerebrovascular disorders.Eur J Nucl Med Mol Imaging. 2020; https://doi.org/10.1007/s00259-020-04697-y
- PET imaging in the differential diagnosis of vascular dementia.J Neurol Sci. 2012; 322: 268-273
- Novel assessment of global metabolism by 18F-FDG-PET for localizing affected lobe in temporal lobe epilepsy.Nucl Med Commun. 2016; 37: 882-887
- 18F-FDG is a superior indicator of cognitive performance compared to 18F-florbetapir in Alzheimer’s disease and mild cognitive impairment evaluation: a global quantitative analysis.J Alzheimers Dis. 2019; 70: 1197-1207
- PET/MRI for neurologic applications.J Nucl Med. 2012; 53: 1916-1925
- Alzheimer’s disease: past, present, and future.J Int Neuropsychol Soc. 2017; 23: 818-831
- Mild cognitive impairment.Clin Geriatr Med. 2017; 33: 325-337
- Suboptimal validity of amyloid imaging-based diagnosis and management of Alzheimer’s disease: why it is time to abandon the approach.Eur J Nucl Med Mol Imaging. 2020; 47: 225-230
- Integrated 18F-fluorodeoxyglucose positron emission tomography magnetic resonance imaging (18F-FDG PET/MRI), a multimodality approach for comprehensive evaluation of dementia patients: a pictorial essay.Indian J Radiol Imaging. 2015; 25: 342-352
- Advances in clinical PET/MRI instrumentation.PET Clin. 2016; 11: 95-103
- Comparison of values of CT and MRI imaging in the diagnosis of hepatocellular carcinoma and analysis of prognostic factors.Oncol Lett. 2019; 17: 1184-1188
- 18)F-NaF and (18)F-FDG as molecular probes in the evaluation of atherosclerosis.Eur J Nucl Med Mol Imaging. 2018; 45: 2190-2200
- PET/MR imaging of atherosclerosis: initial experience and outlook.Am J Nucl Med Mol Imaging. 2013; 3: 393-396
- Imaging atherosclerotic plaque inflammation with [18F]-fluorodeoxyglucose positron emission tomography.Circulation. 2002; 105: 2708-2711
- The role of radionuclide imaging in epilepsy. Part 1: sporadic temporal and extratemporal lobe epilepsy.J Nucl Med Technol. 2017; 45: 14-21
- Validation of FDG-PET/MRI coregistration in nonlesional refractory childhood epilepsy.Epilepsia. 2011; 52: 2216-2224
- Subsequent experience in hybrid PET-MRI for evaluation of refractory focal onset epilepsy.Seizure. 2018; 61: 128-134
- Initial experience in hybrid PET-MRI for evaluation of refractory focal onset epilepsy.Seizure. 2015; 31: 1-4
- Concurrent functional and metabolic assessment of brain tumors using hybrid PET/MR imaging.J Neurooncol. 2016; 127: 287-293
- The neurometabolic cascade of concussion.J Athl Train. 2001; 36: 228-235
- Neuroimaging in patients with head injury.Semin Nucl Med. 2003; 33: 136-147
- FDG-PET imaging in mild traumatic brain injury: a critical review.Front Neuroenergetics. 2014; 5 (Available at:): 13
- Post-concussive symptoms in children with mild traumatic brain injury.Neuropsychology. 2010; 24: 148-159
- [18F]FDG-PET combined with MRI elucidates the pathophysiology of traumatic brain injury in rats.J Neurotrauma. 2016; 34: 1074-1085
- Magnetic resonance-based motion correction for positron emission tomography imaging.Semin Nucl Med. 2013; 43: 60-67
- MR-based cardiac and respiratory motion-compensation techniques for PET-MR imaging.PET Clin. 2016; 11: 179-191
- Motion-corrected whole-heart PET-MR for the simultaneous visualisation of coronary artery integrity and myocardial viability: an initial clinical validation.Eur J Nucl Med Mol Imaging. 2018; 45: 1975-1986
- Correction of respiratory and cardiac motion in cardiac PET/MR using MR-based motion modeling.Phys Med Biol. 2018; 63: 225011
- Performing magnetic resonance imaging in patients with implantable pacemakers and defibrillators: results of a European Heart Rhythm Association survey.Europace. 2012; 14: 1807-1809
- Myocardial perfusion quantification using simultaneously acquired (13) NH3-ammonia PET and dynamic contrast-enhanced MRI in patients at rest and stress.Magn Reson Med. 2018; 80: 2641-2654
- Feasibility of simultaneous PET-MR perfusion using a novel cardiac perfusion phantom.Eur J Hybrid Imaging. 2017; 1: 4
- Hybrid PET/MR imaging of the heart: feasibility and initial results.Radiology. 2013; 268: 366-373
- Targeted imaging of the spatial and temporal variation of matrix metalloproteinase activity in a porcine model of postinfarct remodeling: relationship to myocardial dysfunction.Circ Cardiovasc Imaging. 2011; 4: 381-391
- The future of molecular imaging.JACC Cardiovasc Imaging. 2011; 4: 799-806
- Molecular imaging of the chemokine receptor CXCR4 after acute myocardial infarction.JACC Cardiovasc Imaging. 2015; 8: 1417-1426
- Clinical use of cardiac PET/MRI: current state-of-the-art and potential future applications.Jpn J Radiol. 2018; 36: 313-323
- Prospective evaluation of 18F-fluorodeoxyglucose uptake in postischemic myocardium by simultaneous positron emission tomography/magnetic resonance imaging as a prognostic marker of functional outcome.Circ Cardiovasc Imaging. 2016; 9: e004316
- Detection of acute inflammatory myocarditis in Epstein Barr virus infection using hybrid 18F-fluoro-deoxyglucose–positron emission tomography/magnetic resonance imaging.Circ Am Heart Assoc. 2014; 130: 925-926
- ACCF/ACR/AHA/NASCI/SCMR 2010 expert consensus document on cardiovascular magnetic resonance: a report of the American College of Cardiology Foundation Task Force on Expert Consensus Documents.J Am Coll Cardiol. 2010; 55: 2614-2662
- Coronary artery plaque imaging: comparison of black-blood MRI and 64-multidetector computed tomography.Chronic Dis Transl Med. 2016; 2: 159-165
- F-18 FDG uptake in the large arteries: a new observation.Clin Nucl Med. 2001; 26: 314-319
- FDG-PET is an effective imaging modality to detect and quantify age-related atherosclerosis in large arteries.Eur J Nucl Med Mol Imaging. 2008; 35: 562-569
- Delayed time-point 18F-FDG PET CT imaging enhances assessment of atherosclerotic plaque inflammation.Nucl Med Commun. 2013; 34: 860-867
- 18F-sodium fluoride uptake is a marker of active calcification and disease progression in patients with aortic stenosis.Circ Cardiovasc Imaging. 2014; 7: 371-378
- Common carotid artery molecular calcification assessed by 18F-NaF PET/CT is associated with increased cardiovascular disease risk: results from the CAMONA Study.J Nucl Med. 2017; 58: 34
- Coronary artery PET/MR imaging: feasibility, limitations, and solutions.JACC Cardiovasc Imaging. 2017; 10: 1103-1112
- Histologic diagnostic rate of cardiac sarcoidosis: evaluation of endomyocardial biopsies.Am Heart J. 1999; 138: 299-302
- Cardiac sarcoidosis.J Am Coll Cardiol. 2016; 68: 411-421
- Cardiac sarcoidosis: state of the art review.Cardiovasc Diagn Ther. 2016; 6: 50-63
- Improved detection of cardiac sarcoidosis using magnetic resonance with myocardial T2 mapping.Am J Respir Crit Care Med. 2014; 189: 109-112
- Reduction in (1)(8)F-fluorodeoxyglucose uptake on serial cardiac positron emission tomography is associated with improved left ventricular ejection fraction in patients with cardiac sarcoidosis.J Nucl Cardiol. 2014; 21: 166-174
- Diagnostic accuracy and prognostic value of simultaneous hybrid 18F-fluorodeoxyglucose positron emission tomography/magnetic resonance imaging in cardiac sarcoidosis.Eur Heart J Cardiovasc Imaging. 2018; 19: 757-767
- Diagnosis and treatment response evaluation of cardiac sarcoidosis using positron emission tomography/magnetic resonance imaging.Eur Heart J. 2014; 36: 550
- Usefulness of MRI-assisted metabolic volumetric parameters provided by simultaneous (18)F-fluorocholine PET/MRI for primary prostate cancer characterization.Eur J Nucl Med Mol Imaging. 2015; 42: 1247-1256
- Prospective evaluation of 18F-FACBC PET/CT and PET/MRI versus multiparametric MRI in intermediate- to high-risk prostate cancer patients (FLUCIPRO trial).Eur J Nucl Med Mol Imaging. 2018; 45: 355-364
- Gallium 68 PSMA-11 PET/MR imaging in patients with intermediate- or high-risk prostate cancer.Radiology. 2018; 288: 495-505
- The rise of PSMA ligands for diagnosis and therapy of prostate cancer.J Nucl Med. 2016; 57: 79S-89S
- Optimal MRI sequences for 68Ga-PSMA-11 PET/MRI in evaluation of biochemically recurrent prostate cancer.EJNMMI Res. 2017; 7: 77
- Prostate cancer evaluation using PET quantification in 68Ga-PSMA-11 PET/MR with attenuation correction of bones as a fifth compartment.Quant Imaging Med Surg. 2020; 10: 40-47
- Prediction of microvascular invasion of hepatocellular carcinoma using gadoxetic acid-enhanced MR and 18F-FDG PET/CT.Abdom Imaging. 2015; 40: 843-851
- Multiparametric FDG-PET/MRI of hepatocellular carcinoma: initial experience.Contrast Media Mol Imaging. 2018; 2018: 5638283
- Simultaneous time-of-flight PET/MR identifies the hepatic 90Y-resin distribution after radioembolization.Clin Nucl Med. 2020; 45: e92-e93
- Detection of liver metastases in patients with adenocarcinomas of the gastrointestinal tract: comparison of 18F-FDG PET/CT and MR imaging.Abdom Imaging. 2015; : 1213-1222https://doi.org/10.1007/s00261-014-0283-x
- Qualitative and quantitative image analysis of CT and MR imaging in patients with neuroendocrine liver metastases in comparison to 68 Ga-DOTATOC PET.Eur J Radiol. 2015; : 1593-1600https://doi.org/10.1016/j.ejrad.2015.04.009
- 18 F-FDG PET/MR imaging in patients with suspected liver lesions: value of liver-specific contrast agent gadobenate dimeglumine.PLoS One. 2017; 12: e0180349
- Colorectal cancer liver metastases: diagnostic performance and prognostic value of PET/MR imaging.Radiology. 2016; 280: 782-792
- Diagnostic performance of [18F]FDG-PET/MRI for liver metastasis in patients with primary malignancy: a systematic review and meta-analysis.Eur Radiol. 2019; : 3553-3563https://doi.org/10.1007/s00330-018-5909-x
- Protocol requirements and diagnostic value of PET/MR imaging for liver metastasis detection.Eur J Nucl Med Mol Imaging. 2014; 41: 649-658
- Value of retrospective fusion of PET and MR images in detection of hepatic metastases: comparison with 18F-FDG PET/CT and Gd-EOB-DTPA–enhanced MRI.J Nucl Med. 2010; 51: 692-699
- PET/MR imaging in cancers of the gastrointestinal tract.PET Clin. 2016; 11: 403-423
- Applications of PET-MRI in musculoskeletal disease.J Magn Reson Imaging. 2018; : 27-47https://doi.org/10.1002/jmri.26183
- PET/MR imaging: technical aspects and potential clinical applications.Radiology. 2013; 267: 26-44
- The role of radiological and hybrid imaging for muscle metastases: a systematic review.Eur Radiol. 2019; https://doi.org/10.1007/s00330-019-06555-4
- Musculoskeletal applications of PET/MR.Semin Musculoskelet Radiol. 2014; : 203-216https://doi.org/10.1055/s-0034-1371021
- Nononcologic applications of PET/CT and PET/MRI in musculoskeletal, orthopedic, and rheumatologic imaging: general considerations, techniques, and radiopharmaceuticals.J Nucl Med Technol. 2018; : 33-38https://doi.org/10.2967/jnmt.117.198663
- Applications of PET-computed tomography-magnetic resonance in the management of benign musculoskeletal disorders.PET Clin. 2019; 14: 1-15
- PET/MRI of metabolic activity in osteoarthritis: a feasibility study.J Magn Reson Imaging. 2017; 45: 1736-1745
- 18F-Sodium fluoride PET/CT and PET/MR imaging of bone and joint disorders.PET Clin. 2018; 13: 477-490
- Use of simultaneous 18F-FDG PET/MRI for the detection of spondylodiskitis.J Nucl Med. 2016; 57: 1396-1401
- PET/MRI in infection and inflammation.Semin Nucl Med. 2018; : 225-241https://doi.org/10.1053/j.semnuclmed.2018.02.003
- PET/MR imaging in musculoskeletal disorders.PET Clin. 2016; 11: 453-463
- PET/MR imaging: a critical appraisal [Internet].J Nucl Med. 2014; : 56S-58Shttps://doi.org/10.2967/jnumed.113.129270
- Does PET/MR imaging improve cancer assessments? literature evidence from more than 900 patients.J Nucl Med. 2014; 55: 59S-62S
- 18F-FDG PET/CT and PET/MRI perform equally well in cancer: evidence from studies on more than 2,300 patients.J Nucl Med. 2016; 57: 420-430
- PET and MRI: is the whole greater than the sum of its parts?.Cancer Res. 2016; 76: 6163-6166
- Software-based PET-MR image coregistration: combined PET-MRI for the rest of us!.Pediatr Radiol. 2016; 46: 1552-1561
- Simultaneous whole-body time-of-flight 18F-FDG PET/MRI: a pilot study comparing SUVmax with PET/CT and assessment of MR image quality.Clin Nucl Med. 2015; 40: 1-8
- Simultaneous MR/PET imaging of the human brain: feasibility study.Radiology. 2008; 248: 1028-1035
- A first: simultaneous PET/MR images of the brain debut, increase molecular imaging capabilities.ScienceDaily. 2007; (Available at:)
- Variations in PET/MRI operations: results from an international survey among 39 active sites.J Nucl Med. 2016; 57: 2016-2021
- History and future technical innovation in positron emission tomography.J Med Imaging (Bellingham). 2017; 4: 011013
- A combined PET/CT scanner for clinical oncology.J Nucl Med. 2000; 41: 1369-1379
- A combined PET/CT scanner: the choices.J Nucl Med. 2001; : 533-534
- PET/CT: essentials for clinical practice.Springer Science & Business Media, New York2006
- PET imaging market summary report 2019. IMV Medical Information Division, Arlington2019
- NMR-PET scanner apparatus [Internet]. US Patent.(Available at:) (Accessed February 18, 2020)
- Positron emission tomography/magnetic resonance imaging: the next generation of multimodality imaging?.Semin Nucl Med. 2008; 38: 199-208
- Investigating the state-of-the-art in whole-body MR-based attenuation correction: an intra-individual, inter-system, inventory study on three clinical PET/MR systems.MAGMA. 2016; 29: 75-87
- Current image acquisition options in PET/MR.Semin Nucl Med. 2015; 45: 192-200
- Combined PET/MRI: from status quo to status go. Summary Report of the Fifth International Workshop on PET/MR Imaging; February 15–19, 2016; Tübingen, Germany [Internet].Mol Imaging Biol. 2016; : 637-650https://doi.org/10.1007/s11307-016-0993-2
- Current status of hybrid PET/MRI in oncologic imaging.AJR Am J Roentgenol. 2016; 206: 162-172
- PET/MRI: a luxury or a necessity?.Rev Esp Med Nucl Imagen Mol. 2016; : 313-320https://doi.org/10.1016/j.remnie.2016.07.002
- Clinical PET/MRI: 2018 Update.Am J Roentgenol. 2018; : 295-313https://doi.org/10.2214/ajr.18.20001
- Qualitative and quantitative comparison of PET/CT and PET/MR imaging in clinical practice.J Nucl Med. 2014; 55: 88-94
- An overview of PET/MR, focused on clinical applications.Abdom Radiol (NY). 2017; 42: 631-644
- FDG whole-body PET/MRI in oncology: a systematic review.Nucl Med Mol Imaging. 2017; 51: 22-31
- EANM–ESR white paper on multimodality imaging. A white paper for a black project: towards the decline of nuclear medicine as an independent specialty in Europe? [Internet].Eur J Nucl Med Mol Imaging. 2008; : 674-676https://doi.org/10.1007/s00259-008-0723-3
- A decade of combined imaging: from a PET attached to a CT to a PET inside an MR.Eur J Nucl Med Mol Imaging. 2009; 36 (Springer): 1-2
- A look ahead: PET/MR versus PET/CT.Eur J Nucl Med Mol Imaging. 2009; 36: S3-S9
- From PET/CT to PET/MRI: advances in instrumentation and clinical applications.Mol Pharm. 2014; 11: 3798-3809
- Integrated whole body MR/PET: where are we?.Korean J Radiol. 2015; 16: 32-49
- Combined PET/MR: the real work has just started. Summary Report of the Third International Workshop on PET/MR Imaging; February 17–21, 2014, Tübingen, Germany.Mol Imaging Biol. 2015; : 297-312https://doi.org/10.1007/s11307-014-0818-0
- Practical PET respiratory motion correction in clinical PET/MR.J Nucl Med. 2015; : 890-896https://doi.org/10.2967/jnumed.114.151779
- Comparison of the clinical performance of upper abdominal PET/DCE-MRI with and without concurrent respiratory motion correction (MoCo).Eur J Nucl Med Mol Imaging. 2018; 45: 2147-2154
- Cardiac and respiratory motion correction for simultaneous cardiac PET/MR.J Nucl Med. 2017; 58: 846-852
- MR-based respiratory and cardiac motion correction for PET imaging.Med Image Anal. 2017; 42: 129-144
- Fetal radiation dose from 18F-FDG in pregnant patients imaged with PET, PET/CT, and PET/MR [Internet].J Nucl Med. 2015; : 1218-1222https://doi.org/10.2967/jnumed.115.157032
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Published online: July 14, 2020
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