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Review Article| Volume 1, P251-257, September 2019

Endovascular Management of Acute Lower Extremity Deep Vein Thrombosis

Rationale for Use and Lessons Learned from Emerging Clinical Trials
      Approximately 50% of patients develop postthrombotic syndrome (PTS) after deep vein thrombosis, which can lead to significant impact on quality of life.

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      References

        • Moore P.S.
        • Andrews J.S.
        • Craven T.E.
        • et al.
        Trends in vena caval interruption.
        J Vasc Surg. 2010; 52: 118-125.e3
        • Kesieme E.
        • Kesieme C.
        • Jebbin N.
        • et al.
        Deep vein thrombosis: a clinical review.
        J Blood Med. 2011; 2: 59-69
        • Heit J.A.
        • Spencer F.A.
        • White R.H.
        The epidemiology of venous thromboembolism.
        J Thromb Thrombolysis. 2016; 41: 3-14
        • Deitelzweig S.B.
        • Johnson B.H.
        • Lin J.
        • et al.
        Prevalence of clinical venous thromboembolism in the USA: Current trends and future projections.
        Am J Hematol. 2011; 86: 217-220
        • Kahn S.R.
        • Comerota A.J.
        • Cushman M.
        • et al.
        • American Heart Association Council on Peripheral Vascular Disease
        • Council on Clinical Cardiology, and Council on Cardiovascular and Stroke Nursing
        The postthrombotic syndrome: evidence-based prevention, diagnosis, and treatment strategies: a scientific statement from the American Heart Association.
        Circulation. 2014; 130: 1636-1661
        • Kahn S.R.
        • Shbaklo H.
        • Lamping D.L.
        • et al.
        Determinants of health-related quality of life during the 2 years following deep vein thrombosis.
        J Thromb Haemost. 2008; 6: 1105-1112
        • MacDougall D a
        • Feliu A.L.
        • Boccuzzi S.J.
        • et al.
        Economic burden of deep-vein thrombosis, pulmonary embolism, and post-thrombotic syndrome.
        Am J Health Syst Pharm. 2006; 63: S5-S15
        • Caprini J a
        • Botteman M.F.
        • Stephens J.M.
        • et al.
        Economic burden of long-term complications of deep vein thrombosis after total hip replacement surgery in the United States.
        Value Health. 2003; 6: 59-74
        • Bergan J.J.
        • Schmid-Schönbein G.W.
        • Smith P.D.C.
        • et al.
        Chronic venous disease.
        N Engl J Med. 2006; 355: 488-498
        • Yamaki T.
        • Nozaki M.
        • Sakurai H.
        • et al.
        High peak reflux velocity in the proximal deep veins is a strong predictor of advanced post-thrombotic sequelae.
        J Thromb Haemost. 2007; 5: 305-312
        • Asbeutah A.M.
        • Riha A.Z.
        • Cameron J.D.
        • et al.
        Five-year outcome study of deep vein thrombosis in the lower limbs.
        J Vasc Surg. 2004; 40: 1184-1189
        • Prandoni P.
        • Lensing A.W.
        • Cogo A.
        • et al.
        The long-term clinical course of acute deep venous thrombosis.
        Ann Intern Med. 1996; 125: 1-7
        • Haenen J.H.
        • Janssen M.C.H.
        • Van Langen H.
        • et al.
        The postthrombotic syndrome in relation to venous hemodynamics, as measured by means of duplex scanning and strain-gauge plethysmography.
        J Vasc Surg. 1999; 29: 1071-1076
        • Kahn S.R.
        • Shrier I.
        • Julian J.A.
        • et al.
        Determinants and time course of the postthrombotic syndrome after acute deep venous thrombosis.
        Ann Intern Med. 2008; 149: 698-707
        • Roumen-Klappe E.M.
        • den Heijer M.
        • Janssen M.C.H.
        • et al.
        The post-thrombotic syndrome: incidence and prognostic value of non-invasive venous examinations in a six-year follow-up study.
        Thromb Haemost. 2005; 94: 825-830
        • Prandoni P.
        • Frulla M.
        • Sartor D.
        • et al.
        Venous abnormalities and the post-thrombotic syndrome.
        J Thromb Haemost. 2005; 3: 401-402
        • Soosainathan A.
        • Moore H.M.
        • Gohel M.S.
        • et al.
        Scoring systems for the post-thrombotic syndrome.
        J Vasc Surg. 2013; 57: 254-261
        • Lattimer C.R.
        • Kalodiki E.
        • Azzam M.
        • et al.
        Validation of the Villalta scale in assessing post-thrombotic syndrome using clinical, duplex, and hemodynamic comparators.
        J Vasc Surg Venous Lymphat Disord. 2014; 2: 8-14
        • Kahn S.R.
        • Partsch H.
        • Vedantham S.
        • et al.
        Definition of post-thrombotic syndrome of the leg for use in clinical investigations: a recommendation for standardization.
        J Thromb Haemost. 2009; 7: 879-883
        • Vasquez M.A.
        • Rabe E.
        • McLafferty R.B.
        • et al.
        Revision of the venous clinical severity score: venous outcomes consensus statement: special communication of the American Venous Forum Ad Hoc Outcomes Working Group.
        J Vasc Surg. 2010; 52: 1387-1396
        • Eklof B.
        • Rutherford R.B.
        • Bergan J.J.
        • et al.
        Revision of the CEAP classification for chronic venous disorders: consensus statement.
        J Vasc Surg. 2004; 40: 1248-1252
        • Vedantham S.
        • Goldhaber S.Z.
        • Kahn S.R.
        • et al.
        Rationale and design of the ATTRACT Study: A multicenter randomized trial to evaluate pharmacomechanical catheter-directed thrombolysis for the prevention of postthrombotic syndrome in patients with proximal deep vein thrombosis.
        Am Heart J. 2013; 165: 523-530.e3
        • Plate G.
        • Akesson H.
        • Einarsson E.
        • et al.
        Long-term results of venous thrombectomy combined with a temporary arterio-venous fistula.
        Eur J Vasc Surg. 1990; 4: 483-489
        • Meissner M.H.
        • Manzo R.A.
        • Bergelin R.O.
        • et al.
        Deep venous insufficiency: the relationship between lysis and subsequent reflux.
        J Vasc Surg. 1993; 18: 596-605
        • Hull R.D.
        • Marder V.J.
        • Mah A.F.
        • et al.
        Quantitative assessment of thrombus burden predicts the outcome of treatment for venous thrombosis: a systematic review.
        Am J Med. 2005; https://doi.org/10.1016/j.amjmed.2005.01.025
        • Watson L.
        • Broderick C.
        • Armon M.P.
        Thrombolysis for acute deep vein thrombosis.
        Cochrane Database Syst Rev. 2014; (CD002783)
        • Comerota A.J.
        • Throm R.C.
        • Mathias S.D.
        • et al.
        Catheter-directed thrombolysis for iliofemoral deep venous thrombosis improves health-related quality of life.
        J Vasc Surg. 2000; 32: 130-137
        • AbuRahma A.F.
        • Perkins S.E.
        • Wulu J.T.
        • et al.
        Iliofemoral deep vein thrombosis: conventional therapy versus lysis and percutaneous transluminal angioplasty and stenting.
        Ann Surg. 2001; 233: 752-760
        • Enden T.
        • Kløw N.E.
        • Sandvik L.
        • et al.
        Catheter-directed thrombolysis vs. anticoagulant therapy alone in deep vein thrombosis: Results of an open randomized, controlled trial reporting on short-term patency.
        J Thromb Haemost. 2009; 7: 1268-1275
        • Enden T.
        • Haig Y.
        • Kløw N.E.
        • et al.
        Long-term outcome after additional catheter-directed thrombolysis versus standard treatment for acute iliofemoral deep vein thrombosis (the CaVenT study): a randomised controlled trial.
        Lancet. 2012; 379: 31-38
        • Haig Y.
        • Enden T.
        • Grøtta O.
        • et al.
        • CaVenT Study Group
        Post-thrombotic syndrome after catheter-directed thrombolysis for deep vein thrombosis (CaVent): 5-year follow-up results of an open-label, randomised controlled trial.
        Lancet. 2016; 3: e64-e71
        • Lin P.H.
        • Zhou W.
        • Dardik A.
        • et al.
        Catheter-direct thrombolysis versus pharmacomechanical thrombectomy for treatment of symptomatic lower extremity deep venous thrombosis.
        Am J Surg. 2006; 192: 782-788
        • Vedantham S.
        • Goldhaber S.Z.
        • Julian J.A.
        • et al.
        Pharmacomechanical catheter-directed thrombolysis for deep-vein thrombosis.
        N Engl J Med. 2017; 377: 2240-2252
        • Comerota A.J.
        • Kearon C.
        • Gu C.
        • et al.
        • for the ATTRACT Trial Investigators
        Endovascular thrombus removal for acute iliofemoral deep vein thrombosis: analysis from a stratified multicenter randomized trial.
        Circulation. 2019; 139: 1162-1173
        • Kearon C.
        • Gu C.
        • Julian J.A.
        • et al.
        • for the ATTRACT Trial Investigators
        Pharmacomechanical catheter-directed thrombolysis for acute femoral-popliteal deep-vein thrombosis: analysis from a stratified randomized trial.
        Thromb Haemost. 2019; 19: 633-644